-. Clin Dermatol. What started as a single, quarter-inch raised welt on my left rib cage eventually morphed into two, then four. doi: 10.1111/jdv.17316, PubMed Abstract | CrossRef Full Text | Google Scholar, 2. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. Federal government websites often end in .gov or .mil. (A) Dermoscopic features: dotted and linear vessels forming a network on a yellowish background with some whitish peripheral scales (original magnification x20). "There's some emerging data where there are certain skin rashes that seem to be more associated with the COVID vaccine, and pityriasis rosea is one them. Clipboard, Search History, and several other advanced features are temporarily unavailable. government site. Clinical findings of pityriasis rosealike, Clinical findings of pityriasis rosealike eruption in the patients. 2021 Oct;20(10):3080-3084. doi: 10.1111/jocd.14372. -, Broccolo F., Drago F., Careddu A.M., et al. Before 2022 May;11(2):222-225. doi: 10.7774/cevr.2022.11.2.222. A virus may cause pityriasis rosea, but experts arent sure. At first, I thought it was a mosquito bite. The cause of pityriasis rosea is not known, but it is commonly believed to be caused by a virus or bacteria. 2022 Nov;36(11):1947-1968. doi: 10.1111/jdv.18294. Keywords: Pityriasis Rosea Shortly After mRNA-1273 COVID-19 Vaccination. Oueijan RI, Hill OR, Ahiawodzi PD, Fasinu PS, Thompson DK. Unauthorized use of these marks is strictly prohibited. Here, we described a case of PR-like eruption that developed 14 days after Oxford/AstraZeneca vaccination in a 52-year-old Thai woman with glioblastoma. official website and that any information you provide is encrypted National Library of Medicine Some patients may have a cold before the rash. Case Report: Pityriasis Rosea-Like Eruption Following COVID-19 Vaccination. Histopathological Patterns of Cutaneous Adverse Reaction to Anti-SARS-CoV-2 Vaccines: The Integrative Role of Skin Biopsy. Table 1 summarizes all reported cases of PR-like eruption following COVID-19 vaccination. Med Clin (Barc). Anyone can get pityriasis rosea. Fortunately, PR-like eruption is responsive to topical corticosteroids without any systemic adverse effects. Authors Lina Abdullah 1 Among patients who received inactivated vaccines, another case of PR-like eruption was reported four days after the first dose of CoronaVac (SinoVac) (1). Unfortunately, due to her deteriorating neurologic status, her associated symptoms were not evaluated properly. and transmitted securely. government site. Br J Dermatol. (2006) 12:1. doi: 10.5070/D380D8301D, 11. Akdas E, Ilter N, Ogut B, Erdem O. Pityriasis rosea following CoronaVac COVID-19 vaccination: a case report. The patients/participants provided their written informed consent to participate in this study. Disseminated erythematous-papulosquamous lesions, with right laterocervical herald patch (clinical aspect on admission). The Covid Symptom Study. 2022 Jun;7:164-168. doi: 10.1016/j.jdin.2022.01.009. Pityriasis rosealike rashes have been described after H1N1 influenza, HPV, diphtheria, poliomyelitis, smallpox, pneumococcal, hepatitis B and BCG vaccinations. Ciccarese G, Parodi A, Drago F. SARS-CoV-2 as possible inducer of viral reactivations. Em Rata Just Debuted a Chic Italian Bob With Baby Bangs. Med. You may develop a raised, discolored, circular or oval-shaped patch that ranges from 1 to 6 centimeters (cm). Pityriasis Rosea Induced by COVID-19 Vaccination Eur J Case Rep Intern Med. It has been reported that pityriasis rosea has been triggered by several vaccines, as a rare side-effect. 2022 Oct;49(10):948-956. doi: 10.1111/1346-8138.16482. 2022 Mar 9;35(3):342-343. doi: 10.1080/08998280.2022.2044742. The papulovesicular and pityriasis rosea . Careers. 7 Articles, This article is part of the Research Topic, Creative Commons Attribution License (CC BY), Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. Allure may earn a portion of sales from products that are purchased through our site as part of our Affiliate Partnerships with The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of Cond Nast. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. Most of the rare, severe allergic reactions to these vaccines have occurred in people with a history of allergies. The site is secure. However, pityriasis rosea can look similar to other skin conditions, including: If theres any doubt, your healthcare provider may perform the following tests: In most cases, pityriasis rosea goes away without any treatment in six to eight weeks. Keywords: adverse effect, coronavirus, cutaneous eruptions, immunization, pityriasis rosea, SARS-CoV-2, vaccine, case report, Citation: Leerunyakul K, Pakornphadungsit K and Suchonwanit P (2021) Case Report: Pityriasis Rosea-Like Eruption Following COVID-19 Vaccination. Six cases of pityriasis rosea following SARS-CoV-2 vaccination with BNT162b2. Epub 2022 Oct 17. (2021) 60:11501. Few brownish patches also appeared, suggestive of post-inflammatory hyperpigmentation. Luckily, it's not contagious. 8:752443. doi: 10.3389/fmed.2021.752443. Although the exact pathogenesis of PR remains unknown, the endogenous systemic reactivation of HHV (i.e., type 6 and 7) in the skin has been implicated as a precipitating factor. Before J Eur Acad Dermatol Venereol 2016; 30: 544545. 2021 Jul;85(1):46-55. doi: 10.1016/j.jaad.2021.03.092. Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. Epstein-Barr virus reactivation after COVID-19 vaccination in a young immunocompetent man: a case report. Your skin may develop discolored patches (lesions) that look like scales or dry, crinkly paper. Suchonwanit P, Rojhirunsakool S, Khunkhet S. A randomized, investigator-blinded, controlled, split-scalp study of the efficacy and safety of a 1550-nm fractional erbium-glass laser, used in combination with topical 5% minoxidil versus 5% minoxidil alone, for the treatment of androgenetic alopecia. Br J Dermatol 2020; 183: 431442. Cyrenne BM, Al-Mohammedi F, DeKoven JG, Alhusayen R. Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 vaccine. 2022 Jun;7:164-168. doi: 10.1016/j.jdin.2022.01.009. Epub 2021 Apr 26. It is likely that a new viral trigger of pityriasis rosea is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Cutis. 2023 Feb 9;11(2):397. doi: 10.3390/vaccines11020397. The .gov means its official. Epub 2022 Jun 14. Pityriasis rosea is also known as Christmas tree rash. In: Papadakis MA, McPhee SJ, Bernstein J., eds. One case of pityriasis rosea is reported in a patient infected with COVID-19, and the most commonly reported features are exanthomatous rash, urticaria, chickenpox like vesicles, petechiae, and acute hemorrhagic edema of infancy. -. This site needs JavaScript to work properly. Ad Choices. -, Cyrenne BM, Al-Mohammedi F, DeKoven JG, Alhusayen R. Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 vaccine. "Like a lot of things in dermatology, unfortunately, we're not always sure what causes these rashes," says Lam. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. This site needs JavaScript to work properly. Clipboard, Search History, and several other advanced features are temporarily unavailable. 2021 Aug;185(2):e34. Bathe or shower in lukewarm water. Europe PMC is an archive of life sciences journal literature. Cleveland Clinic is a non-profit academic medical center. Those ensuing spots like the circle of dots that erupted on my back a day after the initial raised welt appeared typically resemble a Christmas tree-like formation. Indian J Dermatol 2016;61:37584. Bookshelf Disclaimer. eCollection 2021. J Am Acad Dermatol. However, there isnt enough research to determine that stress may cause pityriasis rosea. Pityriasis rosea is a common condition that causes discolored patches on your skin. Accessibility Vaccine-induced pityriasis rosea and pityriasis rosea-like eruptions: a review of the literature. Pityriasis rosea is a benign inflammatory rash that starts with a single red rash, also known as the "herald patch," which eventually gives way to a larger, similar-looking rash on the trunk within days or weeks, says dermatologist Corey L. Hartman, founder of Skin Wellness Dermatology in Birmingham, Alabama. This site needs JavaScript to work properly. "Any type of stress on the body can sometimes [cause them, and] any vaccine, not just the COVID one.". Dermatol Ther. J Med Virol. Although histopathologic characteristics of PR are also observed in PR-like lesions, the presence of dyskeratotic keratinocytes, interface dermatitis, and eosinophilic infiltration in the dermis may be more prominent in PR-like eruptions (11). You may initially develop a fever, headache or upper respiratory infection. doi: 10.1111/jdv.17342. For instance, the rash sometimes appears only under the arms or on the flanks. Federal government websites often end in .gov or .mil. Epub 2021 May 29. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. The Moderna and Pfizer-BioNTech COVID-19 vaccines are the first two COVID-19 vaccines authorized by the Food and Drug Administration for emergency use and already have been given to millions of Americans. Histopathologic features: (B) microscopic image at a low power field showing psoriasiform epidermal hyperplasia, perivascular infiltration, and interface dermatitis (hematoxylin-eosin; scale bar represents 100 m); (C) microscopic image at a high power field showing focal spongiotic dermatitis, interface dermatitis, and perivascular infiltration of lymphocytes and eosinophils (hematoxylin-eosin; scale bar represents 40 m). Pityriasis rosea, pityriasis rosea-like eruptions, and herpes zoster in the setting of COVID-19 and COVID-19 vaccination. MeSH Moreover, central dusky-red erythematous was observed on some plaques (Figure 2A). Interventions: Some people develop a few large patches on their skin. Lessons: government site. Numerous scattered erythematous, Pityriasis rosea. Accessibility It is important for physicians to be aware of this self-limited reaction so they can reassure and appropriately counsel patients that it is safe to receive subsequent vaccine doses despite the cutaneous eruption. Urbina F, Das A, Sudy E. Clinical variants of pityriasis rosea. Disclaimer. Epub 2022 May 3. I video-chatted with my dermatologist who asked a few questions: Did I have body aches or flu-like symptoms? Cutaneous Reactions Following COVID-19 Vaccination: A Review of the Current Literature. A woman. eCollection 2022 Feb. Kroumpouzos G, Paroikaki ME, Yumeen S, Bhargava S, Mylonakis E. Microorganisms. All rights reserved. This patch is the herald or mother patch. -, Busto-Leis J.M., Servera-Negre G., Mayor-Ibarguren A., et al. 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. Unauthorized use of these marks is strictly prohibited. I tell my patient to use a gentle non-soap cleanser." These findings were consistent with a diagnosis of PR-like eruption. Federal government websites often end in .gov or .mil. Your California Privacy Rights. Pityriasis Rosea Shortly After mRNA-1273 COVID-19 Vaccination. Pityriasis rosea. McMahon DE, Amerson E, Rosenbach M, Lipoff JB, Moustafa D, Tyagi A, et al. sharing sensitive information, make sure youre on a federal KL and KP collated resources. Int J Dermatol. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). The https:// ensures that you are connecting to the (No.) Dermoscopy showed dotted and linear vessels forming a network on a yellowish background, with some whitish peripheral scales (Figure 3A). You may be more likely to develop it if youre: In some cases, people with pityriasis rosea report that they had significant or long-term stress before developing a rash. Adya KA, Inamadar AC, Albadri W. Post Covid-19 vaccination papulovesicular pityriasis rosea-like eruption in a young male. The most commonly inoculated vaccines include those against smallpox, followed by tuberculosis, poliomyelitis, influenza, and human papillomavirus virus (12, 13). official website and that any information you provide is encrypted How do dermatologists treat pityriasis rosea? But some patients also are developing delayed skin reactions on. What at-home treatments do you recommend? Learning points: eCollection 2022. "It looks very different.". Before The site is secure. Figure 2. Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. Drago F, Ciccarese G, Javor S, et al. Before We present two cases of COVID-19 vaccine-induced pityriasis rosea. Get useful, helpful and relevant health + wellness information. and transmitted securely. Cutaneous Complications of mRNA and AZD1222 COVID-19 Vaccines: A Worldwide Review. Do the medications have any side effects? 2023 Cond Nast. Marcantonio-Santa Cruz OY, Vidal-Navarro A, Pesqu D, Gimnez-Arnau AM, Pujol RM, Martin-Ezquerra G. J Eur Acad Dermatol Venereol. 2022 Nov 1;43(6):555-558. doi: 10.2500/aap.2022.43.220058. doi: 10.1111/jdv.17498. Fried foods, including many fast-food items. Cutis. Cutaneous Reactions Following COVID-19 Vaccination: A Review of the Current Literature. Parakeratosis with minimal acanthosis and spongiosis of the epidermis. 8600 Rockville Pike Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Pityriasis rosea as a cutaneous manifestation of COVID-19 infection J Eur Acad Dermatol Venereol. However, the studies dont conclusively prove that COVID-19 causes pityriasis rosea. 2021;185(2):e34. -, Carballido Vzquez A.M., Morgado B. Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. Before KL drafted the original manuscript. J Am Acad Dermatol. eCollection 2022. Unable to load your collection due to an error, Unable to load your delegates due to an error. Pityriasis rosea-like Covid-arm Erythema multiforme Erythroderma Psoriasis Others Grover-like eruptions Herpes simplex reactivation: 24 1 17 4 2 2 1 1 20 15 9 5 2 1 1 1 3 3: 21.5 0.9 15 3.5 1.8 1.8 0.9 0.9 These strains of the herpes virus arent related to the strains that cause cold sores or genital herpes. The site is secure. Due to the rising incidence of coronavirus disease 2019 (COVID-19) worldwide, mass vaccination has been the cornerstone in preventing viral spread and decreasing morbidity and mortality. J Eur Acad Dermatol Venereol. Rashes should be considered a "key diagnostic sign" of Covid-19, according to a study, which found 8% of people who test positive for the virus have some form of rash. Please enable it to take advantage of the complete set of features! 1 Several vaccines have been developed to fight against COVID19, to prevent the transmission among susceptible individuals and to decrease the morbidity Ramot Y, Nanova K, Faitatziadou SM, Assab DA, Berkun Y, Zlotogorski A. J Dtsch Dermatol Ges. Previously, PR has been reported in temporal association with various viral inoculations. Washrawirul C, Triwatcharikorn J, Phannajit J, Ullman M, Susantitaphong P, Rerknimitr P. J Eur Acad Dermatol Venereol. doi: 10.1111/jdv.17301. government site. Your symptoms dont improve after treatment. Pityriasis lichenoides is a clonal T-cell disorder that may develop in response to foreign antigens (eg, infections or drugs) and may be associated with cutaneous T-cell lymphoma. Epub 2021 Jun 10. Cutaneous Eruptions in the Course of COVID-19 Among Geriatric Patients in a Nursing Home in Poland. At first, I thought it could be a fungal infection like ringworm, a common misdiagnosis, says Hartman, but my dermatologist ruled that out when I mentioned the additional spots erupting on my back via our video chat. However, adverse effects to COVID-19 vaccines, particularly cutaneous reactions, have been reported. Department of Dermatology, Graduate School of Medicine, Kyusyu University, Japan. A 3-cm oval plaque with peripheral scale, larger, MeSH The patches may itch. The herald patch is the telltale sign that your rash could be PR, but there are other common (though not universal) symptoms as well. It was described as "clinically reminiscent" of pityriasis rosea by the authors, from the divisions of dermatology and venereology, pathology, intensive care, and the virology laboratory, of the Hpital Cochin, Paris. 8600 Rockville Pike Influenza viruses and vaccines have triggered pityriasis rosea in some cases.". Pityriasis rosea following CoronaVac COVID-19 vaccination: a case report. Dermatol Ther. 94 PDF Pityriasis rosea and pityriasis rosea-like eruptions: How to distinguish them? Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations. PR is a common self-limited papulosquamous eruption typically presenting with a large solitary pink-colored patch or plaque (i.e., herald patch), followed by secondary eruptions of smaller erythematous patches or plaques with associated peripheral collarette scaling distributed along the cleavage lines of the trunk, forming a Christmas tree pattern (5). Some people who have had cosmetic fillers used to remove . 2022 Jan;114:88-89. doi: 10.1016/j.ijid.2021.10.055. J Med Virol 2021; 93: 1850-1851. American Academy of Dermatology's National Library of Dermatologic Teaching Slides. Careers. While annoyingly itchy, the rash does not cause any serious long-term side effects and is not contagious, unlike the diseases these vaccines protect against. Of the 30 cases found, none experienced severe adverse effects and the rash resolved in an average of 5.6 weeks. The ones found in people with pityriasis rosea are human herpesviruses 6 and 7. Pityriasis rosea, COVID-19 and vaccination: new keys to understand an old acquaintance. Pityriasis rosea developing after COVID-19 vaccination. Pityriasis rosea commonly affects the skin on your trunk, arms or legs. 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. Apply a moisturizer, calamine lotion or a nonprescription . doi: 10.1111/bjd.20143. 2022 Sep-Oct;40(5):586-590. doi: 10.1016/j.clindermatol.2022.01.002. You cant spread pityriasis rosea to another person through unprotected sex or skin-to-skin contact. The available COVID-19 vaccines entail different levels of risk for skin reactions. sharing sensitive information, make sure youre on a federal "And it has a particular [dermatomal] distribution because it's along a nerve," which also presents as fluid-filled blisters, rather than lesions. Authors Jordan E Buckley 1 , Laura N Landis 2 , Ronald P Rapini 1 Affiliations At home, she underwent systemic treatment with antihistamines and topical medication with dermatocorticosteroids. Suchonwanit P, Hector CE, Bin Saif GA, McMichael AJ. Would you like email updates of new search results? doi: 10.1016/j.jdcr.2018.04.002, 12. Women are 50% more likely to develop pityriasis rosea. Of the reported cases, 96.7% were secondary to the Pfizer vaccine, with only 1 reported . -, Drago F, Ciccarese G, Rebora A, Parodi A. sharing sensitive information, make sure youre on a federal The study said the appearance was similar to pityriasis rosea, a common skin condition. HHS Vulnerability Disclosure, Help I put on some hydrocortisone and went to sleep, then woke up with another mark on my side, a couple inches below my armpit. Bethesda, MD 20894, Web Policies doi: 10.1159/000517971. 2020 Jul;33(4):e13730. Unable to load your collection due to an error, Unable to load your delegates due to an error. Epub 2021 May 29. How long will it take my body to clear the rash? See this image and copyright information in PMC. HHS Vulnerability Disclosure, Help The condition is more prevalent in spring and fall. Zendaya Shows Off Her Short Sunshine Curls. Epub 2022 Jun 21. Washrawirul C, Triwatcharikorn J, Phannajit J, Ullman M, Susantitaphong P, Rerknimitr P. J Eur Acad Dermatol Venereol. It said blood spots under the skin might also be present, either as spots or dots or on larger areas. (2019) 34:185764. Even though it is benign, it can cause substantial. The papillary dermis shows melanin incontinence, perivascular lymphocytic infiltrate and rare scattered extravasated red blood cells. . (2021) 35:e5468. doi: 10.1016/j.jaad.2021.03.092, 15. Please enable it to take advantage of the complete set of features! The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). One case of pityriasis rosea is reported in a patient infected with COVID-19, and the most commonly reported features are exanthomatous rash, urticaria, chickenpox like vesicles, petechiae, and acute hemorrhagic edema of infancy. The authors have no conflicts of interests to disclose. A 52-year-old Thai woman with a one-year history of recurrent glioblastoma was admitted to our hospital for a planned targeted therapy. Epub 2022 Jan 31. Welsh E, Cardenas-de la Garza JA, Cuellar-Barboza A, et al. If you have pityriasis rosea, it can generally be well-managed without any treatment. The rash itself usually doesnt blister or bleed, but in many cases, the skin may peel. Careers. (2020) 33:e13650. Bethesda, MD 20894, Web Policies Published by Elsevier Inc. Pityriasis rosea. PMC Children often get infected when someone sneezes or kisses them. The authors suggest more research is necessary. Cutaneous Complications of mRNA and AZD1222 COVID-19 Vaccines: A Worldwide Review. It is usually seen in children, adolescents, and young adults. Bookshelf 2021 Sep;35 (9):e546-e548. Herzum A, Trave I, D'Agostino F, Burlando M, Cozzani E, Parodi A. Clin Exp Vaccine Res. While you don't need to treat the rash, some patients ask for treatment to take care of the following. JAAD Int. In: Kelly A, Taylor SC, Lim HW, et al., eds. 2021 Oct;20(10):3080-3084. doi: 10.1111/jocd.14372. Accessibility Dos Santos PG, Vieira HCVS, Wietholter V, Gallina JP, Andrade TR, Marinowic DR, Zanirati GG, da Costa JC. They were found on hands and feet, showing up as red or purple spots caused by bleeding under the skin. 2021 May;62(2):e333-e334. Policy. The https:// ensures that you are connecting to the Front. If you have a very itchy rash, your healthcare provider may prescribe the following to help relieve your symptoms: There are several over-the-counter products or home remedies that can help stop your rash from itching. Treatment with topical 0.1% triamcinolone acetonide twice per day showed partial response after seven days. The https:// ensures that you are connecting to the 2022 Jul 21;14(7):e27108. National Library of Medicine It was found on younger COVID-19 patients suffering milder forms of the virus. Refined carbohydrates, such as sugar, pastries and white bread. Bethesda, MD 20894, Web Policies Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. J Eur Acad Dermatol Venereol 2020; 34: e436-e437. 8600 Rockville Pike Curr Dermatol Rep. 2022;11(4):289-312. doi: 10.1007/s13671-022-00370-9. Busto-Leis JM, Servera-Negre G, Mayor-Ibarguren A, Sendagorta-Cuds E, Feito-Rodrguez M, Nuo-Gonzlez A, et al. (2016) 30:5445. Similar to other viral outbreaks, people can experience flu-like symptoms like a fever, aches, or a runny nose when the herald patch shows up, Lam says, though I was lucky enough to skip that step. J Eur Acad Dermatol Venereol. -, Broccolo F, Drago F, Careddu AM, et al. Bookshelf Moreover, COVID-19 may solely induce human herpesvirus reactivation through the immunomodulatory ability of SARS-CoV-2 to reactivate latent viruses (8, 9). Common causes of drug-induced PR-like eruptions include angiotensin-converting enzyme inhibitors, non-steroidal anti-inflammatory drugs, and gold. Clinical manifestations and histopathologic findings of reported patients with pityriasis-rosea like eruptions following COVID-19 vaccination. Bethesda, MD 20894, Web Policies Accessibility Unable to load your collection due to an error, Unable to load your delegates due to an error. 6 Called a "herald patch,". Cazzato G, Ambrogio F, Pisani MC, Colagrande A, Arezzo F, Cascardi E, Dellino M, Macorano E, Trilli I, Parente P, Lettini T, Romita P, Marzullo A, Ingravallo G, Foti C. Vaccines (Basel). sharing sensitive information, make sure youre on a federal Pityriasis rosea Gibert type rash in an asymptomatic patient that tested positive for COVID-19. Advertising on our site helps support our mission. National Library of Medicine NCI CPTC Antibody Characterization Program. A team of researchers . The clinics of HHV-6 infection in COVID-19 pandemic: Pityriasis rosea and Kawasaki disease. Various mild and benign cutaneous manifestations of the different forms of the COVID-19 vaccine have been documented. Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. Vote for your favorite beauty products now! This reaction is self-limited and resolves in an average of 5.6 weeks. 2021;185(2):e34. Figure 1. (Unfortunately, I scratched my rash until it bled, so my hyperpigmentation may linger.). Theyre both papulosquoamous (pap-you-lo-skway-miss) disorders, which is a term used to characterize skin disorders according to the presence of raised, discolored, scaly patches of skin. doi: 10.1111/dth.13878, 10. Cutaneous manifestation has been reported in 0.2% of patients infected by COVID-19 in China, and 18 out of 88 patients from Italy. Treatment with topical 0.1% triamcinolone acetonide twice daily showed partial response after seven days. J Eur Acad Dermatol Venereol 2016; 30: 544-545. 2021;184(6):11941195. Keywords: An official website of the United States government. Pityriasis rosea following SARS-CoV-2 vaccination: A case series. Histopathological findings of pityriasis rosealike eruption in patient 1. Adverse cutaneous reactions following COVID-19 vaccines have increased, highlighting not only how SARS-CoV-2 infection but also COVID-19 vaccines may induce adverse cutaneous manifestations. The mechanisms behind these COVID-19-related symptoms remain unclear. doi: 10.1097/MD.0000000000029823. It looked like one, and it certainly itched like one but then more came. doi: 10.1111/jdv.17342, 5. Additional evidence that pityriasis rosea is associated with reactivation of human herpesvirus-6 and -7. (a) Pityriasis rosea (chest, flank, and axilla); (b) pityriasis rosea (back). Last reviewed by a Cleveland Clinic medical professional on 06/17/2022. Authors Elina Khattab 1 , Eirini Christaki 2 , Constantinos Pitsios 1 Affiliations 1 Medical School, University of Cyprus, Nicosia, Cyprus. Global prevalence and clinical manifestations of cutaneous adverse reactions following COVID-19 vaccination: A systematic review and meta-analysis. Drug-induced PR-like eruption accounts for 2% of all cutaneous adverse drug reactions (10). 8 PDF Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of 414 cases D. McMahon, E. Amerson, +11 authors E. Freeman Medicine Kroumpouzos G, Paroikaki ME, Yumeen S, Bhargava S, Mylonakis E. Microorganisms. Its important to pay attention to your skin. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. FOIA In conclusion, we have described the first case of PR-like eruption following ChAdOx1 nCoV-19 (Oxford/AstraZeneca) vaccination. official website and that any information you provide is encrypted An official website of the United States government. A variant called inverse pityriasis rosea can affect the skin on your neck, face, armpits (axillae) and groin, though it isnt common. Moreover, almost all lesions faded with associated post-inflammatory hyperpigmentation (Figure 2B). Like previously reported cutaneous eruptions associated with COVID-19 infection, these cases "raise more questions than . Borgia F, Li Pomi F, Alessandrello C, Vaccaro M, Pioggia G, Gangemi S. J Dermatol. Physicians should be aware that pityriasis rosea is a rare side-effect of COVID-19 vaccination.Pityriasis rosea is self-limiting and no medical treatment is usually required. doi: 10.1111/dth.13730. Ethical review and approval was not required for the study on human participants in accordance with the local legislation and institutional requirements. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine.
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